2017; Physical and Mathematical Sciences, 51(2 (243): 187–192
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CALCULATION OF CENTRAL MOMENTS OF DIFFERENTIAL MELTING CURVE OF DNA MOLECULE

Ruz Khazaryan*

Received: 2025-02-06 · Published: 2017-06-15

© 2017 The Author(s) and the original publisher.

CC BY-NC 4.0 This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
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Original title
CALCULATION OF CENTRAL MOMENTS OF DIFFERENTIAL MELTING CURVE OF DNA MOLECULE
Author
Ruz Khazaryan
Published
2017-06-15
Licence
Creative Commons Attribution-NonCommercial 4.0 International
Original
https://doi.org/10.46991/PYSU:A/2017.51.2.187

Abstract

Central moments of function of the differential melting curve (DMC) of DNA have been calculated through expansion of block DNA DMC to Gaussian components. Calculations showed that the first moment of DNA DMC characterizes the melting temperature, the second is DNA melting interval. Central moments of the third and fourth orders characterize distribution of nucleotides along DNA chain. It was shown that the distribution of nucleotides along DNA chain differs from quasi-arbitrary distribution.
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