Multilayer Anisotropic Thin Film with a Twist
ISSN: 1829-1171
Submitted: 2026-07-17
Natural Sciences, Physics, 2026
THE INTERACTION OF Ag-CONTAINING PORPHYRINS WITH DNA AT HIGH IONIC STRENGTH
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Submitted: 2025-02-28
© 2026 by author(s) and The Gufo Inc.
This work is licensed under Creative Commons Attribution–NonCommercial International License
(CC BY-NC 4.0).
Abstract
UV-VIS spectrophotometry and circular dichroism (CD) methods were applied to study the binding of DNA with three novel Ag-containing porphyrins meso-tetra(4N-allylpyridyl) (AgTAlPyP4), meso-tetra(4N-butylpyridyl) (AgTButPyP4) and meso-tetra(4N-oxyethylpyridyl) (AgTOEtPyP4) at high ionic strength. The binding constant Kb and stoichiometry n were determined from binding isotherms for each ligand–DNA complex. The Gibbs free energy, enthalpy and entropy of binding also were calculated using the values of Kb . Obtained results show that these porphyrins associate with the duplex DNA via outside binding mode.